FierceBiotech | New Heart Drug From Novartis: Will It Raise The Risk of Alzheimer's Disease? Forbes Animal studies, Packer told me, first raised the issue 10-20 years ago. “Fortunately,” he said, “we have actual data from long-term clinical trials (not only PARADIGM-HF but also OVERTURE), showing no increase (and actually a decrease) in dementia ... Investigators link Novartis' would-be cardio blockbuster to Alzheimer's risk |